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Gene Information
Gene ID:300888
Symbol:Tmed3
Full Name:transmembrane emp24 domain containing 3
Alias:MGC94283
Organism:Rattus norvegicus (Rat)
Chromosome:8
Genetic Location:8q31
Physical Location:94590176-94598089 on NC_005107.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 23423    Symbol (Name): TMED3 (transmembrane emp24 protein transport domain containing 3)
Ortholog Status:The human GeneID 23423 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Tmed3
Fold Change:1.15
P Value:0.004
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001004249.1NP_001004249.1NC_005107.2 range: 94590176..94598089, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0033116ER-Golgi intermediate compartment membraneCellular ComponentIEA
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:300888
RGD:1303327
Ensembl:ENSRNOG00000013889
dbSNP:Tmed3