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Gene Information
Gene ID:304709
Symbol:Bfar
Full Name:bifunctional apoptosis regulator
Organism:Rattus norvegicus (Rat)
Chromosome:10
Genetic Location:10q11
Physical Location:48-13314 on NC_005109.2
Gene Type:protein-coding
Human Ortholog:GeneID: 51283    Symbol (Name): BFAR (bifunctional apoptosis regulator)
Ortholog Status:The human GeneID 51283 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Bfar
Fold Change:-1.2
P Value:0.009
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Gene Information
Original ID1:Bfar
Fold Change:-1.24
P Value:0.007
Note:Differential expression between ethanol and water groups in amygdala
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001013125.1NP_001013143.1NC_005109.2 range: 48..13314
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005624membrane fractionCellular ComponentIEA
GO:0005624membrane fractionCellular ComponentISS
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006916anti-apoptosisBiological ProcessISS
GO:0006915apoptosisBiological ProcessIEA
GO:0006916anti-apoptosisBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:304709
RGD:1304791
Ensembl:ENSRNOG00000003151
dbSNP:Bfar