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Gene Information
Gene ID:30836
Symbol:DNTTIP2
Full Name:deoxynucleotidyltransferase, terminal, interacting protein 2
Alias:ERBP|FCF2|HSU15552|LPTS-RP2|MGC163494|RP4-561L24.1|TdIF2
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1p22.1
Physical Location:94107923-94117329 on NC_000001.9, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 99480 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U15552
Fold Change:0.84
P Value:0.01
Dataset Information
Name:12774316
Method:Microarray
Tissue:Temporal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Sokolov et al. J Neurosci Res. (2003) Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence. PubMed
Summary:To identify candidate mechanisms for alcohol abuse, the expression of 12,626 genes was measured in postmortem temporal cortex from 11 subjects with a history of alcohol abuse or dependence, with or without other psychiatric diagnoses and compared pairwise with the expression in 11 nonalcoholic subjects matched for the other psychiatric diagnoses and demographics. Genes were defined to have altered expression in alcohol abuse if: 1) the gene showed decreased expression in at least 10 of 11 subjects with alcohol abuse, or showed increased expression in at least 10 of 11 subjects with this diagnosis compared to matched non-abusers (P<0.007, X2test); or 2) the difference in the mean abuser/non-abuser ratio for the gene from value of 1.0 was significant at P<0.05 (one sample t-test). In subjects with a history of alcohol abuse or dependence, 163 genes were changed significantly.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_014597.3NP_055412.2NC_000001.9 range: 94107923..94117329, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:30836
HGNC:24013
Ensembl:ENSG00000067334
MIM:611199
HPRD:09994
HuGE Navigator:30836
dbSNP:DNTTIP2
GeneCard:DNTTIP2
AceView:DNTTIP2