ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Schip1

Full Name:

schwannomin interacting protein 1

Alias:

Nf2ip|SCHIP-1|Schip-1a|Schip-1b

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

3 E2

Physical Location:

68376428-68430354 on NC_000069.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 29970 Symbol (Name): SCHIP1 (schwannomin interacting protein 1)

Ortholog Status:

The human GeneID 29970 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Schip1
Original ID2:		AI840446

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013928.5	NP_038956.2	NC_000069.5 range: 68376428..68430354

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	ISS (10669747)
GO:0005515	protein binding	Molecular Function	IPI (10669747)
GO:0042803	protein homodimerization activity	Molecular Function	ISS (10669747)