ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Slc30a7

Full Name:

solute carrier family 30 (zinc transporter), member 7

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

2q41

Physical Location:

212088265-212162937 on NC_005101.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 148867 Symbol (Name): SLC30A7 (solute carrier family 30 (zinc transporter), member 7)

Ortholog Status:

The human GeneID 148867 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Slc30a7
Fold Change:		-1.18
P Value:		0.009
Note:		Differential expression between ethanol and water groups in amygdala

Dataset Information

Name:		18405950
Method:		Microarray
Tissue:		Nucleus accumbens and amygdala
Phenotype:		Ethanol self-administration, alcohol-preferring
Publication:		Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:		The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_227612.4	XP_227612.3	NC_005101.2 range: 212088265..212162937, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component	ISS
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005794	Golgi apparatus	Cellular Component	IEA
GO:0005794	Golgi apparatus	Cellular Component	ISS
GO:0016020	membrane	Cellular Component	IEA
GO:0008324	cation transmembrane transporter activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0005385	zinc ion transmembrane transporter activity	Molecular Function	ISS
GO:0005515	protein binding	Molecular Function	ISS
GO:0006829	zinc ion transport	Biological Process	IEA
GO:0006812	cation transport	Biological Process	IEA
GO:0006829	zinc ion transport	Biological Process	ISS