Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:311059
Symbol:March7
Full Name:membrane-associated ring finger (C3HC4) 7
Alias:Axot
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q21
Physical Location:41922567-41954629 on NC_005102.2
Gene Type:protein-coding
Human Ortholog:GeneID: 64844    Symbol (Name): MARCH7 (membrane-associated ring finger (C3HC4) 7)
Ortholog Status:The human GeneID 64844 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:March7
Fold Change:1.16
P Value:0.006
Note:Differential expression between ethanol and water groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001012087.1NP_001012087.1NC_005102.2 range: 41922567..41954629
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0016874ligase activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:311059
RGD:1308993
Ensembl:ENSRNOG00000006241
dbSNP:March7