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Gene Information
Gene ID:312301
Full Name:similar to Zinc finger protein 398 (Zinc finger DNA binding protein p52/p71)
Organism:Rattus norvegicus (Rat)
Genetic Location:4q24
Physical Location:76081461-76093287 on NC_005103.2
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:RGD1304879
Fold Change:1.4
P Value:0
Gene Information
Original ID1:RGD1304879
Fold Change:1.2
P Value:0.0011
Tissue:Frontal cortex
Gene Information
Original ID1:RGD1304879
Fold Change:1.22
P Value:0.0003
Gene Information
Original ID1:RGD1304879
Fold Change:1.39
P Value:0
Tissue:Nucleus accumbens
Gene Information
Original ID1:RGD1304879
Fold Change:1.36
P Value:0.0001
Dataset Information
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001014056.1NP_001014078.1NC_005103.2 range: 76081461..76093287
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:312301