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Gene Information
Gene ID:312678
Symbol:LOC312678
Organism:Rattus norvegicus (Rat)
Chromosome:4
Genetic Location:4q42
Physical Location:156736065-156811990 on NC_005103.2
Gene Type:unknown
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:LOC312678
Fold Change:-1.35
P Value:0.0001
Tissue:Amygdala
Dataset Information
Name:17451403
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XR_005442.1-NC_005103.2 range: 156736065..156811990
Other Database Cross Links
NCBI Entrez Gene:312678
RGD:
Ensembl:
dbSNP:LOC312678