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Gene Information
Gene ID:314352
Symbol:Sel1l
Full Name:sel-1 suppressor of lin-12-like (C. elegans)
Alias:Sel1h
Organism:Rattus norvegicus (Rat)
Chromosome:6
Genetic Location:6q31
Physical Location:115431168-115472861 on NC_005105.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 6400    Symbol (Name): SEL1L (sel-1 suppressor of lin-12-like (C. elegans))
Ortholog Status:The human GeneID 6400 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Sel1h
Fold Change:-1.19
P Value:0.001
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_177933.2NP_808794.2NC_005105.2 range: 115431168..115472861, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005488bindingMolecular FunctionIEA
GO:0007219Notch signaling pathwayBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:314352
RGD:620147
Ensembl:ENSRNOG00000004464
dbSNP:Sel1l