ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HMGB2

Full Name:

high-mobility group box 2

Alias:

HMG2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

4q31

Physical Location:

174489361-174492166 on NC_000004.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 97165 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

HMGB2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002129.2	NP_002120.1	NC_000004.10 range: 174489361..174492166, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000228	nuclear chromosome	Cellular Component	TAS (1551873)
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA (11909973)
GO:0005737	cytoplasm	Cellular Component	IDA (11909973)
GO:0005634	nucleus	Cellular Component	IDA (11909973)
GO:0000793	condensed chromosome	Cellular Component	IDA (12925773)
GO:0000785	chromatin	Cellular Component	IEA
GO:0003697	single-stranded DNA binding	Molecular Function	TAS (11909973)
GO:0003700	transcription factor activity	Molecular Function	TAS (1551873)
GO:0003690	double-stranded DNA binding	Molecular Function	TAS (11909973)
GO:0008301	DNA bending activity	Molecular Function	IDA (8339930)
GO:0048015	phosphoinositide-mediated signaling	Biological Process	NAS (15504738)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (7797075)
GO:0006334	nucleosome assembly	Biological Process	NAS (11909973)
GO:0006325	establishment and/or maintenance of chromatin architecture	Biological Process	NAS (11909973\|15504738)
GO:0006288	base-excision repair, DNA ligation	Biological Process	IDA (9600082)
GO:0006281	DNA repair	Biological Process	TAS (11909973)
GO:0006260	DNA replication	Biological Process	TAS (11909973)
GO:0006268	DNA unwinding during replication	Biological Process	TAS (11909973)