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Gene Information
Gene ID:32352
Symbol:CG32626
Alias:CG11058|unnamed
Organism:Drosophila melanogaster (Fly)
Chromosome:X
Genetic Location:12C6-12C7
Physical Location:13724778-13739862 on NC_004354.3, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 271    Symbol (Name): AMPD2 (adenosine monophosphate deaminase 2 (isoform L))
Ortholog Status:The human GeneID 271 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CG32626
P Value:4.95E-02
Note:Acute up-regulation, have human and mouse orthologs.
Dataset Information
Name:17054780
Method:Microarray
Phenotype:Ethanol response
Publication:Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
Summary:We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_132703.2NP_572931.1NC_004354.3 range: 13724778..13739862, complement
NM_167384.1NP_727739.2NC_004354.3 range: 13724778..13739862, complement
NM_167385.1NP_727740.1NC_004354.3 range: 13724778..13739862, complement
NM_167386.1NP_727741.2NC_004354.3 range: 13724778..13739862, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0003876AMP deaminase activityMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionIPI (17362353)
GO:0009168purine ribonucleoside monophosphate biosynthetic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:32352
FLYBASE:FBgn0052626