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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    34031Pbprp5-28A4-28A4Pbprp5 
    41410CG6908-86E16-86E16CG6908 
    37832CG3907-60B3-60B4CG3907 
    34291Cyp4e3-30C7-30C7Cyp4e3 
    39882CG9669-73D1-73D1CG9669 
    39855Pros26-73B1-73B1Pros26 
    38659CG18586-64F3-64F3CG18586 
    43496Obp99d-99B8-99B8Obp99d 
    40637CG11999-82F10-82F10CG11999 
    38586CG17150-64C1-64C2CG17150 
    42005CG14899-89B18-89B18CG14899 
    40279CG5047-77C6-77C6CG5047 
    35087CG15155-36E6-36E6CG15155 
    32229CG12717-11B16-11B16CG12717 
    31205kz-2F1-2F1kz 
    5740245CR11700-5E5-5E5CG11700 
    43072CG11909-96D2-96D2CG11909 
    43508CG1973-99B10-99B10CG1973 
    33989CG11266-27D5-27D5CG11266 
    33224cbt-21D1-21D1cbt 
    33037Obp19a-19D1-19D1Obp19a 
    37959CG3894-60E1-60E1CG3894 
    38898Arp66B-66B6-66B6Arp66B 
    39462CG10943-69E6-69E6CG10943 
    2768914CG33307-34D7-34D7CG33307 
    34800CG7916-34D7-34D7CG7916 
    33882Pez-26C3-26C3Pez 
    40909alpha-Est1-84D9-84D9alpha-Est1 
    41307CG14694-86C7-86C7CG14694 
    41954sxe2-89B2-89B3sxe2 
    32696Arpc3B-15E3-15E3Arpc3B 
    41217CG34360-85E14-85E14CG12802 
    44254bab2-61F2-61F3bab2 
    42687wge-94C2-94C3CG31151 
    31833CG7246-8C4-8C4CG7246 
    36424sug-49E1-49E1sug 
    40090fz2-75F9-76A1fz2 
    39819CG4753-72E4-72E4CG4753 
    33114Sep1-19F5-19F5Sep1 
    37058CG10911-55B2-55B2CG10911 
    41032hb-85A5-85A5hb 
    32588CG9911-14B9-14B9CG9911 
    38978rhea-66D6-66D7rhea 
    32648spheroide-15A1-15A2CG9675 
    38753Prat2-65D2-65D3Prat2 
    39456CG10754-69E4-69E4CG10754 
    39917rogdi-73E5-73E5rogdi 
    31909CG3106-8F6-8F6CG3106 
    326226CG32647-11C1-11C2CG32647 
    37110GstE5-55C7-55C7GstE5 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all