Dataset DescriptionDataset Name: 17054780
Species: Fly
Method: Microarray
No. of Genes: 530
Phenotype: Ethanol response
Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.Gene list of this dataset (530 genes)
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GeneID | Symbol | Name | Genetic location | Original ID1 | Original ID2 |
34031 | Pbprp5 | - | 28A4-28A4 | Pbprp5 | |
41410 | CG6908 | - | 86E16-86E16 | CG6908 | |
37832 | CG3907 | - | 60B3-60B4 | CG3907 | |
34291 | Cyp4e3 | - | 30C7-30C7 | Cyp4e3 | |
39882 | CG9669 | - | 73D1-73D1 | CG9669 | |
39855 | Pros26 | - | 73B1-73B1 | Pros26 | |
38659 | CG18586 | - | 64F3-64F3 | CG18586 | |
43496 | Obp99d | - | 99B8-99B8 | Obp99d | |
40637 | CG11999 | - | 82F10-82F10 | CG11999 | |
38586 | CG17150 | - | 64C1-64C2 | CG17150 | |
42005 | CG14899 | - | 89B18-89B18 | CG14899 | |
40279 | CG5047 | - | 77C6-77C6 | CG5047 | |
35087 | CG15155 | - | 36E6-36E6 | CG15155 | |
32229 | CG12717 | - | 11B16-11B16 | CG12717 | |
31205 | kz | - | 2F1-2F1 | kz | |
5740245 | CR11700 | - | 5E5-5E5 | CG11700 | |
43072 | CG11909 | - | 96D2-96D2 | CG11909 | |
43508 | CG1973 | - | 99B10-99B10 | CG1973 | |
33989 | CG11266 | - | 27D5-27D5 | CG11266 | |
33224 | cbt | - | 21D1-21D1 | cbt | |
33037 | Obp19a | - | 19D1-19D1 | Obp19a | |
37959 | CG3894 | - | 60E1-60E1 | CG3894 | |
38898 | Arp66B | - | 66B6-66B6 | Arp66B | |
39462 | CG10943 | - | 69E6-69E6 | CG10943 | |
2768914 | CG33307 | - | 34D7-34D7 | CG33307 | |
34800 | CG7916 | - | 34D7-34D7 | CG7916 | |
33882 | Pez | - | 26C3-26C3 | Pez | |
40909 | alpha-Est1 | - | 84D9-84D9 | alpha-Est1 | |
41307 | CG14694 | - | 86C7-86C7 | CG14694 | |
41954 | sxe2 | - | 89B2-89B3 | sxe2 | |
32696 | Arpc3B | - | 15E3-15E3 | Arpc3B | |
41217 | CG34360 | - | 85E14-85E14 | CG12802 | |
44254 | bab2 | - | 61F2-61F3 | bab2 | |
42687 | wge | - | 94C2-94C3 | CG31151 | |
31833 | CG7246 | - | 8C4-8C4 | CG7246 | |
36424 | sug | - | 49E1-49E1 | sug | |
40090 | fz2 | - | 75F9-76A1 | fz2 | |
39819 | CG4753 | - | 72E4-72E4 | CG4753 | |
33114 | Sep1 | - | 19F5-19F5 | Sep1 | |
37058 | CG10911 | - | 55B2-55B2 | CG10911 | |
41032 | hb | - | 85A5-85A5 | hb | |
32588 | CG9911 | - | 14B9-14B9 | CG9911 | |
38978 | rhea | - | 66D6-66D7 | rhea | |
32648 | spheroide | - | 15A1-15A2 | CG9675 | |
38753 | Prat2 | - | 65D2-65D3 | Prat2 | |
39456 | CG10754 | - | 69E4-69E4 | CG10754 | |
39917 | rogdi | - | 73E5-73E5 | rogdi | |
31909 | CG3106 | - | 8F6-8F6 | CG3106 | |
326226 | CG32647 | - | 11C1-11C2 | CG32647 | |
37110 | GstE5 | - | 55C7-55C7 | GstE5 | |
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