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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    41573CG5724-87C8-87C8CG5724 
    43385Hrb98DE-98D6-98D6Hrb98DE 
    32088CG11727-10B11-10B14CG11727 
    40897alpha-Est9-84D9-84D9alpha-Est9 
    40655CG12162-83A4-83A4CG12162 
    33812CG34381-26A1-26A1CG14004 
    36769CG8400-52D14-52D15CG8400 
    117361v(2)k05816-23C5-23C5v(2)k05816 
    42320CG3739-92A3-92A3CG3739 
    50320dpr12-42A1-42A1dpr12 
    35853Jon44E-44E2-44E2Jon44E 
    37428CG10505-57D7-57D8CG10505 
    34003CG13784-27E4-27E5CG13784 
    34921CG4587-35D3-35D3CG4587 
    34767B4-34C3-34C4B4 
    44920Hsp70Ab-87A3-87A3Hsp70Ab 
    37081CG10916-55B11-55B12CG10916 
    250710Proct-28D2-28D2Proct 
    38363CG32485-63A5-63A5CG32485 
    38830CG8560-65F11-65F11CG8560 
    31464CG3239-5A1-5A1CG3239 
    36595CG12505-50F6-50F6CG12505 
    53436c11.1-8D4-8D5c11.1 
    33073Ser6-19E5-19E5Ser6 
    326130CG31272-86C5-86C5CG31272 
    36385CG17760-49B9-49B10CG17760 
    38747dikar-65C3-65C3dikar 
    42292CG6040-91F2-91F2CG6040 
    326251CG33096-96B21-96B21CG33096 
    37112GstE7-55C7-55C7GstE7 
    39106path-67B10-67B10pathetic 
    43601CG9733-99E3-99E3CG9733 
    39881TSG101-73D1-73D1TSG101 
    246637CG30475-51D5-51D5CG30475 
    42684CG6972-94C1-94C2CG6972 
    42072CG5246-89F1-89F1CG5246 
    117419Irbp-86E4-86E4Irbp 
    40170Mi-2-76D3-76D4Mi-2 
    45329RpL12-60B7-60B7RpL12 
    34489CG17127-32A5-32A5CG17127 
    318066CG34120--CG1819 
    5740294CG41520--CG17443 
    41894CG18522-88F7-88F7CG18522 
    39727CG32150-72A2-72A2CG32150 
    32275mew-11E3-11E8mew 
    5740462CG34398-29F4-29F4CG9487 
    31524CG3011-5C7-5C7CG3011 
    2768935CG33305-32D5-32D5CG33305 
    36020CG1516-46B4-46B4CG1516 
    33683CG15627-25A8-25A8CG15627 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all