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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    42340CG16718-92A11-92A11CG16718 
    36666Cyp6a8-51D1-51D1Cyp6a8 
    47895Nmdmc-85C3-85C3Nmdmc 
    40940dsx-84E5-84E6dsx 
    32261rad-11E1-11E1rad 
    40326CG10581-78A5-78A5CG10581 
    40853CG31248-84C4-84C4CG31248 
    31461CG15784-4F10-4F10CG15784 
    35505scarface-41F6-41F8scarface 
    44297ome-70F1-70F4ome 
    36779Jhedup-52E5-52E5CG8424 
    35544CG8343-42A13-42A13CG8343 
    45285Dr-99B3-99B3Dr 
    33103CG1718-19F3-19F3CG1718 
    40737Pbprp3-83D1-83D1Pbprp3 
    39530CG8745-70C4-70C5CG8745 
    35478gus-41D3-41D3gus 
    41053CG11776-85B1-85B1CG11776 
    41044CG9801-85A9-85A10CG9801 
    31612CG3168-6C9-6C10CG3168 
    31826rdgA-8B7-8B7rdgA 
    35425Grp1-40A1-40A2Grp1 
    31174CG4199-2C9-2C10CG4199 
    37482LBR-57F10-57F11LBR 
    32470Scamp-13C3-13C3Scamp 
    38647CG10575-64E7-64E7CG10575 
    36767CG8397-52D14-52D14CG8397 
    41880CG31302-88F3-88F4CG31302 
    246567CG30364-44C4-44C4CG30364 
    43231Rb97D-97D3-97D3Rb97D 
    46058l(2)05070-52D13-52D14l(2)05070 
    36936CG15917-54A1-54A1CG15917 
    42089CG5319-90A4-90A4CG5319 
    36893CG6429-53D15-53D15CG6429 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all