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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    34031Pbprp5-28A4-28A4Pbprp5 
    41410CG6908-86E16-86E16CG6908 
    37832CG3907-60B3-60B4CG3907 
    34291Cyp4e3-30C7-30C7Cyp4e3 
    39882CG9669-73D1-73D1CG9669 
    39855Pros26-73B1-73B1Pros26 
    38659CG18586-64F3-64F3CG18586 
    43496Obp99d-99B8-99B8Obp99d 
    40637CG11999-82F10-82F10CG11999 
    38586CG17150-64C1-64C2CG17150 
    42005CG14899-89B18-89B18CG14899 
    40279CG5047-77C6-77C6CG5047 
    35087CG15155-36E6-36E6CG15155 
    32229CG12717-11B16-11B16CG12717 
    31205kz-2F1-2F1kz 
    5740245CR11700-5E5-5E5CG11700 
    43072CG11909-96D2-96D2CG11909 
    43508CG1973-99B10-99B10CG1973 
    33989CG11266-27D5-27D5CG11266 
    33224cbt-21D1-21D1cbt 
    33037Obp19a-19D1-19D1Obp19a 
    37959CG3894-60E1-60E1CG3894 
    38898Arp66B-66B6-66B6Arp66B 
    39462CG10943-69E6-69E6CG10943 
    2768914CG33307-34D7-34D7CG33307 
    34800CG7916-34D7-34D7CG7916 
    33882Pez-26C3-26C3Pez 
    40909alpha-Est1-84D9-84D9alpha-Est1 
    41307CG14694-86C7-86C7CG14694 
    41954sxe2-89B2-89B3sxe2 
    32696Arpc3B-15E3-15E3Arpc3B 
    41217CG34360-85E14-85E14CG12802 
    44254bab2-61F2-61F3bab2 
    42687wge-94C2-94C3CG31151 
    31833CG7246-8C4-8C4CG7246 
    36424sug-49E1-49E1sug 
    40090fz2-75F9-76A1fz2 
    39819CG4753-72E4-72E4CG4753 
    33114Sep1-19F5-19F5Sep1 
    37058CG10911-55B2-55B2CG10911 
    41032hb-85A5-85A5hb 
    32588CG9911-14B9-14B9CG9911 
    38978rhea-66D6-66D7rhea 
    32648spheroide-15A1-15A2CG9675 
    38753Prat2-65D2-65D3Prat2 
    39456CG10754-69E4-69E4CG10754 
    39917rogdi-73E5-73E5rogdi 
    31909CG3106-8F6-8F6CG3106 
    326226CG32647-11C1-11C2CG32647 
    37110GstE5-55C7-55C7GstE5 
    37547CG5819-58D3-58D3CG5819 
    40835Antp-84A6-84B2Antp 
    42295CG5629-91F3-91F4CG5629 
    38995h-66D10-66D10h 
    45883kar-87C5-87C5kar 
    38772CG14823-65E3-65E3CG14823 
    31711CG1530-7C8-7C9CG1530 
    41882CG6125-88F4-88F4CG6125 
    318664CG31288-96D1-96D1CG31288 
    37276CG16898-56F4-56F4CG16898 
    31849Ost48-8C14-8C14Ost48 
        CG31653 
    37357CG17999-57B3-57B3CG17999 
    31952CG2962-9B4-9B4CG2962 
    318890p24-2-85E4-85E4CG33105 
    318594CG31106-96C5-96C6CG31106 
    37625CG9826-59B2-59B2CG9826 
    2768730CG12158-45D1-45D1CG12158 
    38124CG9119-61F3-61F3CG9119 
    44631Ag5r-12F4-12F4Ag5r 
    41010CG31259-85A2-85A2CG31259 
    3354941CG40178--CG40178 
    34205CG9466-29F1-29F1CG9466 
    34879yellow-c-35B8-35B8yellow-c 
    37770CG4797-60A2-60A2CG4797 
    39062PGRP-LA-67B1-67B1PGRP-LA 
    35056CG6453-36C10-36C10CG6453 
    2768852par-1-56D9-56D11par-1 
    50205CG16926-56D14-56D14CG16926 
    43769pan-102A3-102A4pan 
    33350CG18317-22B1-22B1CG18317 
    37973Dll-60E2-60E2Dll 
    33583odd-24A1-24A1odd 
    50060CG17618-94C4-94C4CG17618 
    41347RpL3-86D8-86D8RpL3 
    33545CG8837-23E3-23E4CG8837 
    40093nes-76A3-76A3nes 
    33435oaf-22F4-22F4oaf 
    36489Ser8-50A8-50A8Ser8 
    33438Cyp309a1-22F4-23A1Cyp309a1 
    37575Dnr1-58E9-58F1Dnr1 
    40896alpha-Est10-84D8-84D9alpha-Est10 
    43622Jon99Fi-99F6-99F6Jon99Fi 
    35587Cyp6a2-42D1-42D1Cyp6a2 
    34898CG15263-35D1-35D1CG15263 
    41945GATAe-89A12-89A12GATAe 
    31726CG2254-7D5-7D5CG2254 
    33547CG3285-23E4-23E4CG3285 
    42492AnnIX-93B9-93B10AnnIX 
    34647CG6579-33D2-33D3CG6579 
    40136lush-76B9-76B9lush 
    33570CG15414-23F3-23F3CG15414 
    41333Ugt35b-86D5-86D5Ugt35b 
    2768718CG33472-47F13-47F13CG33472 
    42337CG17752-92A10-92A10CG17752 
    42987Nmnat-96B11-96B11CG13645 
    37744l(2)efl-59F6-59F6l(2)efl 
        CG15893 
    33132CG14619-20B1-20B3CG14619 
    35801pnut-44C2-44C2pnut 
    39411Pbprp1-69B4-69B4Pbprp1 
    32544Gbeta13F-13F16-13F16Gbeta13F 
    45588Pdp1-66A14-66A17Pdp1 
    36266Damm-48C5-48C5Damm 
    33266CG13949-21E2-21E2CG13949 
    2768687LpR1-96F1-96F2LpR1 
    35355CG9336-38F3-38F3CG9336 
    32343CG33174-12C4-12C5CG33174 
    31388CG11444-4C7-4C7CG11444 
    33884CG9497-26C3-26C3CG9497 
    326258CG33109-88A12-88A12CG33109 
    34569salm-32F1-32F2salm 
    31035CG14632-1D2-1D2CG14632 
    42363CG17186-92B4-92B4CG17186 
    36318Cyp6t3-48E7-48E8Cyp6t3 
    35861PGRP-SC1b-44E2-44E2PGRP-SC1b 
    36040TER94-46D1-46D1TER94 
    37039olf186-M-54F1-54F1olf186-M 
    41512CG17639-87B9-87B9CG17639 
    30991CG18273-1B4-1B5CG18273 
    45815Spn27A-26F5-26F6Spn27A 
    41503GstD1-87B8-87B8GstD1 
    34708Sir2-34A7-34A7Sir2 
    42416MtnC-92E4-92E4MtnC 
    42169PP2A-B'-90F4-90F5PP2A-B 
    36865Picot-53C15-53D1Picot 
    5740252Not1-45F1-45F4CG1874 
    33317a5-22A1-22A1a5 
    37627CG13531-59B2-59B3CG13531 
    32191Pkcdelta-11A10-11A11Pkcdelta 
    35020CG13283-36B2-36B2CG13283 
    3346192CG33528-50A14-50B1CG33528 
    33098CG32521-19F2-19F3CG32521 
    41291fau-86C6-86C6fau 
    39625mnd-71A4-71B1mnd 
    36471CG4716-49F13-49F13CG4716 
    37480HmgZ-57F9-57F9HmgZ 
    45233capt-21F1-21F1capt 
    43182CG12290-97A6-97A6CG12290 
    47173Men-87C6-87C7Men 
    34919CG7631-35D3-35D3CG7631 
    3772692Menl-2-53C4-53C4CG30097 
    31678CHES-1-like-7B6-7B6CHES-1-like 
    43420CG1443-98F5-98F5CG1443 
    34112CG8486-28F1-28F1CG8486 
    35123CG10383-37A1-37A1CG10383 
    39960CG7542-74D4-74D4CG7542 
    40292Pitslre-77E6-77E6Pitslre 
    35970Pdk-45D5-45D7Pdk 
    59177Tsp42Eb-42E4-42E4Tsp42Eb 
    32564CG8931-14A5-14A5CG8931 
    42023CG14893-89D5-89D5CG14893 
    37737CG17664-59F4-59F4CG17664 
    40961CG7891-84E13-84E13CG7891 
    42338CG16727-92A10-92A10CG16727 
    31957alpha-Man-I-9B5-9B7alpha-Man-I 
    33187CG13693-21B5-21B5CG13693 
    42929CG6643-96A7-96A7CG6643 
    53515Myo28B1-28C1-28C1Myo28B1 
    39415CG32103-69B4-69B5CG32103 
    35881Ggamma1-44F3-44F5Ggamma1 
    36833CG6262-53C2-53C2CG6262 
    36592CG34379-50F4-50F4CG8603 
    35774sut1-44A4-44A4sut1 
    32225Smr-11B10-11B14Smr 
    32561mmd-14A1-14A3mmd 
    38783CG8628-65E4-65E4CG8628 
    43303CG13978-98A1-98A2CG13978 
    40977CG11672-84F9-84F9CG11672 
    44029Aly-84B2-84B2Aly 
    43530CG7824-99C4-99C4CG7824 
    38828CG8562-65F11-65F11CG8562 
    43383fkh-98D5-98D5fkh 
    35494CG30437-41F1-41F1CG30437 
    33466CG3077-23A5-23A5CG3077 
    33346cpb-22B1-22B1cpb 
    39423CG10657-69C3-69C3CG10657 
    33324NLaz-22A1-22A1NLaz 
    41168Scm-85E2-85E2Scm 
    49808Spn1-42D6-42D6Spn1 
    42257CG7720-91C6-91D1CG7720 
    35792CG8708-44B5-44B7CG8708 
    32671ppk28-15A9-15A10ppk28 
    34129CG14277-28F5-28F5CG14277 
    40127CG32210-76B6-76B7CG32210 
    42234CG7695-91B6-91B6CG7695 
    40874Pbprp4-84D3-84D3Pbprp4 
    32285IP3K2-11E11-11E11CG12724 
    42695CG4771-94C4-94C4CG4771 
    41670B52-87F7-87F7B52 
    35359CG9339-38F3-38F5CG9339 
    43127Tsp96F-96F5-96F5Tsp96F 
    38534Cip4-64B1-64B2Cip4 
    32649CG9673-15A2-15A3CG9673 
    38255CG5687-62B11-62B11CG5687 
    50432Peritrophin-15b-29C1-29C1Peritrophin-15b 
    34844elB-35B1-35B1elB 
    32858Cyp18a1-17D1-17D1Cyp18a1 
    38988CG6416-66D9-66D9CG6416 
    43177CG31324-96F14-97A1CG31324 
    37923CG11414-60D5-60D5CG11414 
    32352CG32626-12C6-12C7CG32626 
    42512CG10824-93C2-93C2CG10824 
    39386CG5642-68F6-68F6CG5642 
    31201Vinc-2E2-2E3Vinc 
    31185Pgd-2D4-2D4Pgd 
    34159CG13393-29B4-29B4CG13393 
    326170CG31886-29F5-29F5CG31886 
    38895Ect4-66B5-66B5Ect4 
    32876Pvf1-17E1-17E1Pvf1 
    33045mal-19D1-19D1mal 
    41635CG8774-87E4-87E5CG8774 
    39573CG7768-70D4-70D4CG7768 
    32312Tango13-12A4-12A6CG15758 
    33195CG17078-21B7-21B7CG17078 
    35064CG15145-36C11-36C11CG15145 
    326270MtnD-92F1-92F1MtnD 
    32127CG15221-10E1-10E1CG15221 
    34287CG4364-30C5-30C6CG4364 
    42294Cyp12a4-91F3-91F3Cyp12a4 
    43350CG5508-98B6-98B6CG5508 
    38528Hexo1-64A12-64A12Hexo1 
    318967CG31829-35C5-35C5CG31829 
    39588CG9238-70E1-70E2CG9238 
    42731CG6733-94D13-94D13CG6733 
    5740235RhoGAP1A--RhoGAP1A 
    33695CG3036-25B1-25B2CG3036 
    42066cher-89E12-89E13cher 
    34039Slob-28C1-28C1Slob 
    34805Ance-34E2-34E2Ance 
    50096Spase12-99B1-99B1CG11500 
    3772247CG33671-49B10-49B10CG33671 
    36395CG8776-49B11-49C1CG8776 
    41248Timp-86A1-86A1Timp 
    37109GstE4-55C7-55C7GstE4 
    36244CG9003-48B2-48B2CG9003 
    3355079CG40045--CG40045 
    41198CG12946-85E8-85E8CG12946 
    39750mib1-72C2-72C2mib1 
    34041CG18585-28C1-28C1CG18585 
    36819JhI-26-53B1-53B1JhI-26 
    44095fus-52B3-52B5fus 
    38691CG6602-65A5-65A5CG6602 
    32354CG34346-12C7-12C7CG11072 
    42634mats-94A12-94A12mats 
    36182CG13215-47E1-47E1CG13215 
    42638CG34376-94A14-94A15CG13845 
    38038CG16971-61B2-61B2CG16971 
    42353CG11391-92B2-92B2CG11391 
    40117CG9449-76B5-76B5CG9449 
    38382CG32278-63B8-63B8CG32278 
    37230hts-56D3-56D5hts 
    35332Hr38-38D5-38E3Hr38 
    41372CG6764-86E5-86E5CG6764 
    34872mol-35B7-35B8mol 
    40833Scr-84A5-84A5Scr 
    37165Mctp--Mctp 
    32955CG14207-18D3-18D3CG14207 
    39085aay-67B5-67B5aay 
    37055CG5767-55B1-55B2CG5767 
    41135CG8147-85D18-85D18CG8147 
    2768673att-ORFB-92F1-92F1att-ORFB 
    37131Pepck-55D3-55D3Pepck 
    44258ps-85D16-85D17ps 
    43602CG9682-99E3-99E3CG9682 
    33166CG11377-21B2-21B2CG11377 
    40666CG2519-83B1-83B1CG2519 
    38565Rpd3-64B12-64B12Rpd3 
    33040Pbprp2-19D1-19D1Pbprp2 
    40143wnd-76B9-76B9CG8789 
    2768965asparagine-synthetase-78C1-78C2asparagine-synthetase 
        Pinocchio 
    37449Fkbp13-57E6-57E6Fkbp13 
    32245fne-11D3-11D4fne 
    37459CG15673-57F3-57F3CG15673 
    39906a10-73E4-73E4a10 
    38221CG7995-62B1-62B1CG7995 
    44117bgm-34F1-34F1bgm 
    34012ninaC-27F3-27F3ninaC 
    39008CG13311-66D15-66D15CG13311 
    44154Hmgs-53C1-53C1Hmgs 
    38523CG1311-64A12-64A12CG1311 
    32458Top1-13B6-13B6Top1 
    39132CG6767-67C4-67C5CG6767 
    48338GstD5-87B8-87B8GstD5 
    3772597alphagamma-element:CR32865-87B13-87B13alphagamma-element:CR32865 
    33571tim-23F6-23F6tim 
    37340CG16799-57A9-57A9CG16799 
    32952CG14205-18D3-18D3CG14205 
    49228mod(mdg4)-93D7-93D9mod(mdg4) 
    31565Top3beta-5E5-5E5Top3 
    33354CG17646-22B1-22B2CG17646 
    2768717CheB42b-42E1-42E1CheB42b 
    42659CG33110-94B4-94B4CG33110 
    3346209Ddr-26C1-26C2Ddr 
    37487CG13492-58A2-58A2CG13492 
    39191Or67d-67D12-67D12Or67d 
    42819ofs-95B9-95C1CG10192 
    44548lola-47A11-47A13lola 
    32382CG13404-12E6-12E6CG13404 
    37539CG3290-58D1-58D1CG3290 
    33896Tig-26D1-26D1Tig 
    31239egh-3A6-3A6egh 
    33170CG4822-21B2-21B2CG4822 
    43050CG11878-96C8-96C8CG11878 
    31405ctp-4C13-4C14ctp 
    33903CG9535-26D7-26D7CG9535 
    33754Cyp4ac1-25D2-25D2Cyp4ac1 
    39691CG7656-71E1-71E1CG7656 
    43291mrt-97F1-97F1mrt 
    318916CG33181-7F1-7F1CG32714 
    41313Sodh-2-86C7-86C7Sodh-2 
    37966CG3589-60E1-60E1CG3589 
    42460CG17838-92F12-93A1CG17838 
    32058antdh-10A10-10A10antdh 
    4379864CG34110--CG13662 
    33265kraken-21E2-21E2kraken 
    34137CG7830-29A3-29A3CG7830 
    39572nuf-70D3-70D4nuf 
    42125CG7523-90C1-90C1CG7523 
    44274disp-83C5-83C5disp 
    246444CG30083-52C2-52C2CG30083 
    33277ia2-21E3-21E3ia2 
    34042CG7025-28C1-28C1CG7025 
    35837Cyp6a13-44D3-44D3Cyp6a13 
    39533CG34400-70C5-70C5CG32131 
    326151pgant5-25C4-25C5pgant5 
    35439CG6675-40E3-40E3CG6675 
    35613Tsp42Ed-42E5-42E5Tsp42Ed 
    3772382cp309-71B2-71B4cp309 
    35314CG31688-38C6-38C7CG31688 
    35766Odc1-44A2-44A2Odc1 
    39716comm2-71F1-71F1comm2 
    44226Xbp1-57C3-57C4Xbp1 
    59167CG18806-38A8-38A8CG18806 
    32687CG9086-15C5-15C6CG9086 
    41391CG6791-86E11-86E11CG6791 
    35372CG9259-39A1-39A1CG9259 
    33422CG15390-22E1-22E1CG15390 
        CG15281 
    5740557CG34365-52A1-52A1CG18625 
    31557CG3585-5E1-5E3CG3585 
    50323CG15210-9F4-9F4CG15210 
    40468laza-79E4-79E4CG11440 
    36464CG4670-49F11-49F11CG4670 
    34030CG6630-28A1-28A1CG6630 
    36217etaTry-47F3-47F3etaTry 
    45757beta'Cop-34B9-34B9beta'Cop 
    33569Thor-23F3-23F3Thor 
    50170Teh3-64A10-64A10CG18676 
    36080Syb-46F8-46F8Syb 
    31782CG12116-7F1-7F1CG12116 
    47082Adf1-42C3-42C3Adf1 
    46155CG31195-92F12-92F13CG31195 
    48481l(1)dd4-12B4-12B4l(1)dd4 
    35555jing-42B3-42B3jing 
    326208CG32344-61C1-61C1CG32344 
    40650Or83b-83A2-83A2Or83b 
    42866Mpk2-95E5-95E5Mpk2 
    38513ImpL2-64A10-64A10ImpL2 
    32485Ac13E-13C7-13C8Ac13E 
    38546CG15021-64B6-64B6CG15021 
    43250CG6283-97D14-97D14CG6283 
    42380Hs6st-92B9-92C1Hs6st 
    2769001zormin-62C4-62D1CG32310 
    37576CG3927-58F1-58F1CG3927 
    38006gol-60F3-60F3gol 
    32174CG32656-11A2-11A3CG32656 
    46246Pglym87-87B3-87B3Pglym87 
    41252CG3996-86A2-86A2CG3996 
    33477Duox-23B2-23B2CG3131 
    40267CG5932-77C4-77C4CG5932 
    3354863CG12423--CG12423 
    34226Try29F-29F7-29F7Try29F 
    46085l(2)08717-55F3-55F4l(2)08717 
    50433Peritrophin-15a-29C1-29C1Peritrophin-15a 
    32629CG9784-14F2-14F2CG9784 
    34686MRP-33F3-33F4CG6214 
    48317ttk-100D1-100D1ttk 
    40856CG14610-84C6-84C6CG14610 
    38470CG14985-64A3-64A3CG14985 
    32941CoRest-18C8-18C8CG33525 
    39577CG13482-70D5-70D5CG13482 
    38196n-syb-62A9-62A9n-syb 
    36319CG8858-48E8-48E8CG8858 
    40942Os-C-84E6-84E6Os-C 
    38411CG12016-63D1-63D1CG12016 
    37983CG2857-60E5-60E5CG2857 
    37451MESK2-57E8-57E9MESK2 
    44072ran-10A8-10A8ran 
    50003PQBP-1-84F16-85A1CG31369 
    34565mre11-32E2-32E2mre11 
    32439CG9065-13A9-13A9CG9065 
    42017CG10345-89D5-89D5CG10345 
    40263CG11796-77C3-77C3CG11796 
    44001Sucb-64D3-64D3Sucb 
    35410CG17570-38C3-38C3CG17570 
    44851raw-29E4-29E6raw 
    318914CG31720-31B1-31B1CG31720 
    41272Cyp12e1-86B4-86B4Cyp12e1 
    41231Fancl-85F8-85F8CG12812 
    34203CG9463-29F1-29F1CG9463 
    43797Pur-alpha-102C2-102C2Pur-alpha 
    37729Dcp-1-59E3-59E3Dcp-1 
    5740252Not1-45F1-45F4CG1884 
    38252CG1887-62B9-62B9CG1887 
    42796CG31148-95A8-95A8CG31148 
    37144CG5482-55E2-55E3CG5482 
    37917CG13592-60D4-60D4CG13592 
    41133CG9363-85D17-85D17CG9363 
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