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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    34919CG7631-35D3-35D3CG7631 
    3772692Menl-2-53C4-53C4CG30097 
    31678CHES-1-like-7B6-7B6CHES-1-like 
    43420CG1443-98F5-98F5CG1443 
    34112CG8486-28F1-28F1CG8486 
    35123CG10383-37A1-37A1CG10383 
    39960CG7542-74D4-74D4CG7542 
    40292Pitslre-77E6-77E6Pitslre 
    35970Pdk-45D5-45D7Pdk 
    59177Tsp42Eb-42E4-42E4Tsp42Eb 
    32564CG8931-14A5-14A5CG8931 
    42023CG14893-89D5-89D5CG14893 
    37737CG17664-59F4-59F4CG17664 
    40961CG7891-84E13-84E13CG7891 
    42338CG16727-92A10-92A10CG16727 
    31957alpha-Man-I-9B5-9B7alpha-Man-I 
    33187CG13693-21B5-21B5CG13693 
    42929CG6643-96A7-96A7CG6643 
    53515Myo28B1-28C1-28C1Myo28B1 
    39415CG32103-69B4-69B5CG32103 
    35881Ggamma1-44F3-44F5Ggamma1 
    36833CG6262-53C2-53C2CG6262 
    36592CG34379-50F4-50F4CG8603 
    35774sut1-44A4-44A4sut1 
    32225Smr-11B10-11B14Smr 
    32561mmd-14A1-14A3mmd 
    38783CG8628-65E4-65E4CG8628 
    43303CG13978-98A1-98A2CG13978 
    40977CG11672-84F9-84F9CG11672 
    44029Aly-84B2-84B2Aly 
    43530CG7824-99C4-99C4CG7824 
    38828CG8562-65F11-65F11CG8562 
    43383fkh-98D5-98D5fkh 
    35494CG30437-41F1-41F1CG30437 
    33466CG3077-23A5-23A5CG3077 
    33346cpb-22B1-22B1cpb 
    39423CG10657-69C3-69C3CG10657 
    33324NLaz-22A1-22A1NLaz 
    41168Scm-85E2-85E2Scm 
    49808Spn1-42D6-42D6Spn1 
    42257CG7720-91C6-91D1CG7720 
    35792CG8708-44B5-44B7CG8708 
    32671ppk28-15A9-15A10ppk28 
    34129CG14277-28F5-28F5CG14277 
    40127CG32210-76B6-76B7CG32210 
    42234CG7695-91B6-91B6CG7695 
    40874Pbprp4-84D3-84D3Pbprp4 
    32285IP3K2-11E11-11E11CG12724 
    42695CG4771-94C4-94C4CG4771 
    41670B52-87F7-87F7B52 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all