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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    37547CG5819-58D3-58D3CG5819 
    40835Antp-84A6-84B2Antp 
    42295CG5629-91F3-91F4CG5629 
    38995h-66D10-66D10h 
    45883kar-87C5-87C5kar 
    38772CG14823-65E3-65E3CG14823 
    31711CG1530-7C8-7C9CG1530 
    41882CG6125-88F4-88F4CG6125 
    318664CG31288-96D1-96D1CG31288 
    37276CG16898-56F4-56F4CG16898 
    31849Ost48-8C14-8C14Ost48 
        CG31653 
    37357CG17999-57B3-57B3CG17999 
    31952CG2962-9B4-9B4CG2962 
    318890p24-2-85E4-85E4CG33105 
    318594CG31106-96C5-96C6CG31106 
    37625CG9826-59B2-59B2CG9826 
    2768730CG12158-45D1-45D1CG12158 
    38124CG9119-61F3-61F3CG9119 
    44631Ag5r-12F4-12F4Ag5r 
    41010CG31259-85A2-85A2CG31259 
    3354941CG40178--CG40178 
    34205CG9466-29F1-29F1CG9466 
    34879yellow-c-35B8-35B8yellow-c 
    37770CG4797-60A2-60A2CG4797 
    39062PGRP-LA-67B1-67B1PGRP-LA 
    35056CG6453-36C10-36C10CG6453 
    2768852par-1-56D9-56D11par-1 
    50205CG16926-56D14-56D14CG16926 
    43769pan-102A3-102A4pan 
    33350CG18317-22B1-22B1CG18317 
    37973Dll-60E2-60E2Dll 
    33583odd-24A1-24A1odd 
    50060CG17618-94C4-94C4CG17618 
    41347RpL3-86D8-86D8RpL3 
    33545CG8837-23E3-23E4CG8837 
    40093nes-76A3-76A3nes 
    33435oaf-22F4-22F4oaf 
    36489Ser8-50A8-50A8Ser8 
    33438Cyp309a1-22F4-23A1Cyp309a1 
    37575Dnr1-58E9-58F1Dnr1 
    40896alpha-Est10-84D8-84D9alpha-Est10 
    43622Jon99Fi-99F6-99F6Jon99Fi 
    35587Cyp6a2-42D1-42D1Cyp6a2 
    34898CG15263-35D1-35D1CG15263 
    41945GATAe-89A12-89A12GATAe 
    31726CG2254-7D5-7D5CG2254 
    33547CG3285-23E4-23E4CG3285 
    42492AnnIX-93B9-93B10AnnIX 
    34647CG6579-33D2-33D3CG6579 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all