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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    36819JhI-26-53B1-53B1JhI-26 
    44095fus-52B3-52B5fus 
    38691CG6602-65A5-65A5CG6602 
    32354CG34346-12C7-12C7CG11072 
    42634mats-94A12-94A12mats 
    36182CG13215-47E1-47E1CG13215 
    42638CG34376-94A14-94A15CG13845 
    38038CG16971-61B2-61B2CG16971 
    42353CG11391-92B2-92B2CG11391 
    40117CG9449-76B5-76B5CG9449 
    38382CG32278-63B8-63B8CG32278 
    37230hts-56D3-56D5hts 
    35332Hr38-38D5-38E3Hr38 
    41372CG6764-86E5-86E5CG6764 
    34872mol-35B7-35B8mol 
    40833Scr-84A5-84A5Scr 
    37165Mctp--Mctp 
    32955CG14207-18D3-18D3CG14207 
    39085aay-67B5-67B5aay 
    37055CG5767-55B1-55B2CG5767 
    41135CG8147-85D18-85D18CG8147 
    2768673att-ORFB-92F1-92F1att-ORFB 
    37131Pepck-55D3-55D3Pepck 
    44258ps-85D16-85D17ps 
    43602CG9682-99E3-99E3CG9682 
    33166CG11377-21B2-21B2CG11377 
    40666CG2519-83B1-83B1CG2519 
    38565Rpd3-64B12-64B12Rpd3 
    33040Pbprp2-19D1-19D1Pbprp2 
    40143wnd-76B9-76B9CG8789 
    2768965asparagine-synthetase-78C1-78C2asparagine-synthetase 
        Pinocchio 
    37449Fkbp13-57E6-57E6Fkbp13 
    32245fne-11D3-11D4fne 
    37459CG15673-57F3-57F3CG15673 
    39906a10-73E4-73E4a10 
    38221CG7995-62B1-62B1CG7995 
    44117bgm-34F1-34F1bgm 
    34012ninaC-27F3-27F3ninaC 
    39008CG13311-66D15-66D15CG13311 
    44154Hmgs-53C1-53C1Hmgs 
    38523CG1311-64A12-64A12CG1311 
    32458Top1-13B6-13B6Top1 
    39132CG6767-67C4-67C5CG6767 
    48338GstD5-87B8-87B8GstD5 
    3772597alphagamma-element:CR32865-87B13-87B13alphagamma-element:CR32865 
    33571tim-23F6-23F6tim 
    37340CG16799-57A9-57A9CG16799 
    32952CG14205-18D3-18D3CG14205 
    49228mod(mdg4)-93D7-93D9mod(mdg4) 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all