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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    35359CG9339-38F3-38F5CG9339 
    43127Tsp96F-96F5-96F5Tsp96F 
    38534Cip4-64B1-64B2Cip4 
    32649CG9673-15A2-15A3CG9673 
    38255CG5687-62B11-62B11CG5687 
    50432Peritrophin-15b-29C1-29C1Peritrophin-15b 
    34844elB-35B1-35B1elB 
    32858Cyp18a1-17D1-17D1Cyp18a1 
    38988CG6416-66D9-66D9CG6416 
    43177CG31324-96F14-97A1CG31324 
    37923CG11414-60D5-60D5CG11414 
    32352CG32626-12C6-12C7CG32626 
    42512CG10824-93C2-93C2CG10824 
    39386CG5642-68F6-68F6CG5642 
    31201Vinc-2E2-2E3Vinc 
    31185Pgd-2D4-2D4Pgd 
    34159CG13393-29B4-29B4CG13393 
    326170CG31886-29F5-29F5CG31886 
    38895Ect4-66B5-66B5Ect4 
    32876Pvf1-17E1-17E1Pvf1 
    33045mal-19D1-19D1mal 
    41635CG8774-87E4-87E5CG8774 
    39573CG7768-70D4-70D4CG7768 
    32312Tango13-12A4-12A6CG15758 
    33195CG17078-21B7-21B7CG17078 
    35064CG15145-36C11-36C11CG15145 
    326270MtnD-92F1-92F1MtnD 
    32127CG15221-10E1-10E1CG15221 
    34287CG4364-30C5-30C6CG4364 
    42294Cyp12a4-91F3-91F3Cyp12a4 
    43350CG5508-98B6-98B6CG5508 
    38528Hexo1-64A12-64A12Hexo1 
    318967CG31829-35C5-35C5CG31829 
    39588CG9238-70E1-70E2CG9238 
    42731CG6733-94D13-94D13CG6733 
    5740235RhoGAP1A--RhoGAP1A 
    33695CG3036-25B1-25B2CG3036 
    42066cher-89E12-89E13cher 
    34039Slob-28C1-28C1Slob 
    34805Ance-34E2-34E2Ance 
    50096Spase12-99B1-99B1CG11500 
    3772247CG33671-49B10-49B10CG33671 
    36395CG8776-49B11-49C1CG8776 
    41248Timp-86A1-86A1Timp 
    37109GstE4-55C7-55C7GstE4 
    36244CG9003-48B2-48B2CG9003 
    3355079CG40045--CG40045 
    41198CG12946-85E8-85E8CG12946 
    39750mib1-72C2-72C2mib1 
    34041CG18585-28C1-28C1CG18585 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all