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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    40136lush-76B9-76B9lush 
    33570CG15414-23F3-23F3CG15414 
    41333Ugt35b-86D5-86D5Ugt35b 
    2768718CG33472-47F13-47F13CG33472 
    42337CG17752-92A10-92A10CG17752 
    42987Nmnat-96B11-96B11CG13645 
    37744l(2)efl-59F6-59F6l(2)efl 
        CG15893 
    33132CG14619-20B1-20B3CG14619 
    35801pnut-44C2-44C2pnut 
    39411Pbprp1-69B4-69B4Pbprp1 
    32544Gbeta13F-13F16-13F16Gbeta13F 
    45588Pdp1-66A14-66A17Pdp1 
    36266Damm-48C5-48C5Damm 
    33266CG13949-21E2-21E2CG13949 
    2768687LpR1-96F1-96F2LpR1 
    35355CG9336-38F3-38F3CG9336 
    32343CG33174-12C4-12C5CG33174 
    31388CG11444-4C7-4C7CG11444 
    33884CG9497-26C3-26C3CG9497 
    326258CG33109-88A12-88A12CG33109 
    34569salm-32F1-32F2salm 
    31035CG14632-1D2-1D2CG14632 
    42363CG17186-92B4-92B4CG17186 
    36318Cyp6t3-48E7-48E8Cyp6t3 
    35861PGRP-SC1b-44E2-44E2PGRP-SC1b 
    36040TER94-46D1-46D1TER94 
    37039olf186-M-54F1-54F1olf186-M 
    41512CG17639-87B9-87B9CG17639 
    30991CG18273-1B4-1B5CG18273 
    45815Spn27A-26F5-26F6Spn27A 
    41503GstD1-87B8-87B8GstD1 
    34708Sir2-34A7-34A7Sir2 
    42416MtnC-92E4-92E4MtnC 
    42169PP2A-B'-90F4-90F5PP2A-B 
    36865Picot-53C15-53D1Picot 
    5740252Not1-45F1-45F4CG1874 
    33317a5-22A1-22A1a5 
    37627CG13531-59B2-59B3CG13531 
    32191Pkcdelta-11A10-11A11Pkcdelta 
    35020CG13283-36B2-36B2CG13283 
    3346192CG33528-50A14-50B1CG33528 
    33098CG32521-19F2-19F3CG32521 
    41291fau-86C6-86C6fau 
    39625mnd-71A4-71B1mnd 
    36471CG4716-49F13-49F13CG4716 
    37480HmgZ-57F9-57F9HmgZ 
    45233capt-21F1-21F1capt 
    43182CG12290-97A6-97A6CG12290 
    47173Men-87C6-87C7Men 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all