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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    5740557CG34365-52A1-52A1CG18625 
    31557CG3585-5E1-5E3CG3585 
    50323CG15210-9F4-9F4CG15210 
    40468laza-79E4-79E4CG11440 
    36464CG4670-49F11-49F11CG4670 
    34030CG6630-28A1-28A1CG6630 
    36217etaTry-47F3-47F3etaTry 
    45757beta'Cop-34B9-34B9beta'Cop 
    33569Thor-23F3-23F3Thor 
    50170Teh3-64A10-64A10CG18676 
    36080Syb-46F8-46F8Syb 
    31782CG12116-7F1-7F1CG12116 
    47082Adf1-42C3-42C3Adf1 
    46155CG31195-92F12-92F13CG31195 
    48481l(1)dd4-12B4-12B4l(1)dd4 
    35555jing-42B3-42B3jing 
    326208CG32344-61C1-61C1CG32344 
    40650Or83b-83A2-83A2Or83b 
    42866Mpk2-95E5-95E5Mpk2 
    38513ImpL2-64A10-64A10ImpL2 
    32485Ac13E-13C7-13C8Ac13E 
    38546CG15021-64B6-64B6CG15021 
    43250CG6283-97D14-97D14CG6283 
    42380Hs6st-92B9-92C1Hs6st 
    2769001zormin-62C4-62D1CG32310 
    37576CG3927-58F1-58F1CG3927 
    38006gol-60F3-60F3gol 
    32174CG32656-11A2-11A3CG32656 
    46246Pglym87-87B3-87B3Pglym87 
    41252CG3996-86A2-86A2CG3996 
    33477Duox-23B2-23B2CG3131 
    40267CG5932-77C4-77C4CG5932 
    3354863CG12423--CG12423 
    34226Try29F-29F7-29F7Try29F 
    46085l(2)08717-55F3-55F4l(2)08717 
    50433Peritrophin-15a-29C1-29C1Peritrophin-15a 
    32629CG9784-14F2-14F2CG9784 
    34686MRP-33F3-33F4CG6214 
    48317ttk-100D1-100D1ttk 
    40856CG14610-84C6-84C6CG14610 
    38470CG14985-64A3-64A3CG14985 
    32941CoRest-18C8-18C8CG33525 
    39577CG13482-70D5-70D5CG13482 
    38196n-syb-62A9-62A9n-syb 
    36319CG8858-48E8-48E8CG8858 
    40942Os-C-84E6-84E6Os-C 
    38411CG12016-63D1-63D1CG12016 
    37983CG2857-60E5-60E5CG2857 
    37451MESK2-57E8-57E9MESK2 
    44072ran-10A8-10A8ran 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all