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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    31565Top3beta-5E5-5E5Top3 
    33354CG17646-22B1-22B2CG17646 
    2768717CheB42b-42E1-42E1CheB42b 
    42659CG33110-94B4-94B4CG33110 
    3346209Ddr-26C1-26C2Ddr 
    37487CG13492-58A2-58A2CG13492 
    39191Or67d-67D12-67D12Or67d 
    42819ofs-95B9-95C1CG10192 
    44548lola-47A11-47A13lola 
    32382CG13404-12E6-12E6CG13404 
    37539CG3290-58D1-58D1CG3290 
    33896Tig-26D1-26D1Tig 
    31239egh-3A6-3A6egh 
    33170CG4822-21B2-21B2CG4822 
    43050CG11878-96C8-96C8CG11878 
    31405ctp-4C13-4C14ctp 
    33903CG9535-26D7-26D7CG9535 
    33754Cyp4ac1-25D2-25D2Cyp4ac1 
    39691CG7656-71E1-71E1CG7656 
    43291mrt-97F1-97F1mrt 
    318916CG33181-7F1-7F1CG32714 
    41313Sodh-2-86C7-86C7Sodh-2 
    37966CG3589-60E1-60E1CG3589 
    42460CG17838-92F12-93A1CG17838 
    32058antdh-10A10-10A10antdh 
    4379864CG34110--CG13662 
    33265kraken-21E2-21E2kraken 
    34137CG7830-29A3-29A3CG7830 
    39572nuf-70D3-70D4nuf 
    42125CG7523-90C1-90C1CG7523 
    44274disp-83C5-83C5disp 
    246444CG30083-52C2-52C2CG30083 
    33277ia2-21E3-21E3ia2 
    34042CG7025-28C1-28C1CG7025 
    35837Cyp6a13-44D3-44D3Cyp6a13 
    39533CG34400-70C5-70C5CG32131 
    326151pgant5-25C4-25C5pgant5 
    35439CG6675-40E3-40E3CG6675 
    35613Tsp42Ed-42E5-42E5Tsp42Ed 
    3772382cp309-71B2-71B4cp309 
    35314CG31688-38C6-38C7CG31688 
    35766Odc1-44A2-44A2Odc1 
    39716comm2-71F1-71F1comm2 
    44226Xbp1-57C3-57C4Xbp1 
    59167CG18806-38A8-38A8CG18806 
    32687CG9086-15C5-15C6CG9086 
    41391CG6791-86E11-86E11CG6791 
    35372CG9259-39A1-39A1CG9259 
    33422CG15390-22E1-22E1CG15390 
        CG15281 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all