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Dataset Description
  • Dataset Name: 17054780
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 530
  • Phenotype: Ethanol response
  • Publication: Morozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
  • Dataset Summary: We assessed whole-genome transcriptional responses following alcohol exposure and demonstrate immediate down-regulation of genes affecting olfaction, rapid upregulation of biotransformation enzymes and, concomitant with development of tolerance, altered transcription of transcriptional regulators, proteases and metabolic enzymes, including biotransformation enzymes and enzymes associated with fatty acid biosynthesis. Functional tests of P-element disrupted alleles corresponding to genes with altered transcription implicated 75% of these in the response to alcohol, two-thirds of which have human orthologues. We performed analysis of variance to identify probe sets with significant differences in expression between the three treatments, and a false positive discovery rate of q < 0.05 to account for multiple tests.

    Gene list of this dataset (530 genes)
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    50003PQBP-1-84F16-85A1CG31369 
    34565mre11-32E2-32E2mre11 
    32439CG9065-13A9-13A9CG9065 
    42017CG10345-89D5-89D5CG10345 
    40263CG11796-77C3-77C3CG11796 
    44001Sucb-64D3-64D3Sucb 
    35410CG17570-38C3-38C3CG17570 
    44851raw-29E4-29E6raw 
    318914CG31720-31B1-31B1CG31720 
    41272Cyp12e1-86B4-86B4Cyp12e1 
    41231Fancl-85F8-85F8CG12812 
    34203CG9463-29F1-29F1CG9463 
    43797Pur-alpha-102C2-102C2Pur-alpha 
    37729Dcp-1-59E3-59E3Dcp-1 
    5740252Not1-45F1-45F4CG1884 
    38252CG1887-62B9-62B9CG1887 
    42796CG31148-95A8-95A8CG31148 
    37144CG5482-55E2-55E3CG5482 
    37917CG13592-60D4-60D4CG13592 
    41133CG9363-85D17-85D17CG9363 
    36129CG7220-47B7-47B9CG7220 
    31021CG5273-1C4-1C4CG5273 
    36780Jhe-52E5-52E5Jhe 
    32095Spase25-10B15-10B16CG1751 
    43827RfaBp-102D3-102D4RfaBp 
    31587Spat-6B1-6B1Spat 
    37544Oatp58Db-58D2-58D2Oatp58Db 
    41117CG8129-85D12-85D13CG8129 
    34916CG15253-35D3-35D3CG15253 
    40924CG2993-84E1-84E1CG2993 
    31591CG34417-6B2-6B3CG3950 
    40738Os-E-83D1-83D1Os-E 
    39556CG6661-70C15-70C15CG6661 
    42598CG5778-94A2-94A2CG5778 
    36391CG8785-49B10-49B11CG8785 
    39005CG5804-66D14-66D14CG5804 
    39933Mip-74A5-74A5Mip 
    31873CG17754-8D3-8D3CG17754 
    43358CG4849-98B6-98B6CG4849 
    42319CG18493-92A3-92A3CG18493 
    34557Ca-beta-32D5-32E1Ca-beta 
    31251per-3B1-3B2per 
    35687CG1600-43D2-43D3CG1600 
    41570CG12279-87C6-87C6CG12279 
    37929pio-60D7-60D8piopio 
    39225Cpr67Fb-67F1-67F1CG18348 
    40633Hph-82F7-82F8Hph 
    41469CG14741-87A7-87A7CG14741 
    37782CG4585-60A5-60A5CG4585 
    41605ry-87D9-87D9ry 
    Page: 1 2 3 4 5 6 7 8 9 10 11 list all