ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HPD

Full Name:

4-hydroxyphenylpyruvate dioxygenase

Alias:

4-HPPD|4HPPD|GLOD3|PPD

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

12q24-qter

Physical Location:

120761815-120781151 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Fly: 40263 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

HPD

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002150.2	NP_002141.1	NC_000012.10 range: 120761815..120781151, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006559	L-phenylalanine catabolic process	Biological Process	IEA
GO:0006572	tyrosine catabolic process	Biological Process	TAS (7851880)
GO:0009072	aromatic amino acid family metabolic process	Biological Process	IEA