ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HSPB1

Full Name:

heat shock 27kDa protein 1

Alias:

CMT2F|DKFZp586P1322|HMN2B|HS.76067|HSP27|HSP28|Hsp25

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

7q11.23

Physical Location:

75769858-75771547 on NC_000007.12

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Z23090
Fold Change:		2.62

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001540.2	NP_001531.1	NC_000007.12 range: 75769858..75771547

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	TAS (16130169)
GO:0005856	cytoskeleton	Cellular Component	TAS (16130169)
GO:0009986	cell surface	Cellular Component	IEP (12493773)
GO:0042802	identical protein binding	Molecular Function	IPI (11003656)
GO:0006446	regulation of translational initiation	Biological Process	TAS (10859165)
GO:0006916	anti-apoptosis	Biological Process	TAS (16130169)
GO:0006928	cell motility	Biological Process	TAS (16130169)
GO:0006986	response to unfolded protein	Biological Process	TAS (10859165)