ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

3565

Symbol:

IL4

Full Name:

interleukin 4

Alias:

BSF1|IL-4|MGC79402

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

5q31.1

Physical Location:

132037271-132046266 on NC_000005.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 16189 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

IL4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000589.2	NP_000580.1	NC_000005.8 range: 132037271..132046266
NM_172348.1	NP_758858.1	NC_000005.8 range: 132037271..132046266

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	TAS (11418631)
GO:0005136	interleukin-4 receptor binding	Molecular Function	TAS (11418631)
GO:0005515	protein binding	Molecular Function	IPI (8266078)
GO:0045189	connective tissue growth factor biosynthetic process	Biological Process	TAS (11967989)
GO:0045191	regulation of isotype switching	Biological Process	TAS (11418631)
GO:0045348	positive regulation of MHC class II biosynthetic process	Biological Process	ISS
GO:0045671	negative regulation of osteoclast differentiation	Biological Process	ISS
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	ISS
GO:0048295	positive regulation of isotype switching to IgE isotypes	Biological Process	ISS
GO:0048304	positive regulation of isotype switching to IgG isotypes	Biological Process	ISS
GO:0043066	negative regulation of apoptosis	Biological Process	ISS
GO:0042325	regulation of phosphorylation	Biological Process	ISS
GO:0042102	positive regulation of T cell proliferation	Biological Process	ISS
GO:0042092	T-helper 2 type immune response	Biological Process	TAS (11676128)
GO:0030890	positive regulation of B cell proliferation	Biological Process	ISS
GO:0030183	B cell differentiation	Biological Process	TAS (11418631)
GO:0008203	cholesterol metabolic process	Biological Process	ISS (11971948)
GO:0006968	cellular defense response	Biological Process	TAS (10725748)
GO:0006935	chemotaxis	Biological Process	TAS (10725748)
GO:0050776	regulation of immune response	Biological Process	ISS