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Gene Information
Gene ID:3574
Symbol:IL7
Full Name:interleukin 7
Alias:IL-7
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8q12-q13
Physical Location:79807559-79880312 on NC_000008.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:IL7
Original ID2:J04156
Dataset Information
Name:11093800
Method:Microarray
Tissue:SH-SY5Y neuroblastoma cells
Phenotype:Ethanol response
Publication:Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000880.2NP_000871.1NC_000008.9 range: 79807559..79880312, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentIEA
GO:0005576extracellular regionCellular ComponentTAS (2643102)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005139interleukin-7 receptor bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (8266077)
GO:0005139interleukin-7 receptor bindingMolecular FunctionTAS (2643102)
GO:0045453bone resorptionBiological ProcessISS
GO:0043066negative regulation of apoptosisBiological ProcessISS
GO:0030890positive regulation of B cell proliferationBiological ProcessISS
GO:0009887organ morphogenesisBiological ProcessTAS (2643102)
GO:0008284positive regulation of cell proliferationBiological ProcessTAS (2643102)
GO:0007267cell-cell signalingBiological ProcessTAS (2643102)
GO:0006959humoral immune responseBiological ProcessTAS (2643102)
GO:0006955immune responseBiological ProcessIEA
GO:0045582positive regulation of T cell differentiationBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:3574
HGNC:6023
Ensembl:ENSG00000104432
MIM:146660
HPRD:00892
HuGE Navigator:3574
dbSNP:IL7
GeneCard:IL7
AceView:IL7