ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

IL10RA

Full Name:

interleukin 10 receptor, alpha

Alias:

CDW210A|HIL-10R|IL-10R1|IL10R

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q23

Physical Location:

117362318-117377403 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 16154 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

NM_001558

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001558.2	NP_001549.1	NC_000011.8 range: 117362318..117377403

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	TAS (8407942)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0004872	receptor activity	Molecular Function	TAS (8407942)
GO:0004920	interleukin-10 receptor activity	Molecular Function	TAS (8120391)
GO:0005515	protein binding	Molecular Function	IPI (11485736\|15837194)