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Gene Information
Gene ID:362242
Symbol:Snta1
Full Name:syntrophin, acidic 1
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q41
Physical Location:144843676-144874234 on NC_005102.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 6640    Symbol (Name): SNTA1 (syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component))
Ortholog Status:The human GeneID 6640 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Snta1
Fold Change:1.12
P Value:0.007
Note:Differential expression between ethanol and saccharin groups in nucleus accumbens
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_342548.3XP_342549.2NC_005102.2 range: 144843676..144874234, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042383sarcolemmaCellular ComponentISS
GO:0045211postsynaptic membraneCellular ComponentISS
GO:0005515protein bindingMolecular FunctionIPI
GO:0030165PDZ domain bindingMolecular FunctionIPI (15024025)
GO:0007528neuromuscular junction developmentBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:362242
RGD:1307068
Ensembl:ENSRNOG00000016062
dbSNP:Snta1