ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ITPKA

Full Name:

inositol 1,4,5-trisphosphate 3-kinase A

Alias:

IP3KA

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

15q14-q21

Physical Location:

39573413-39583038 on NC_000015.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 228550 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002220.1	NP_002211.1	NC_000015.8 range: 39573413..39583038

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005516	calmodulin binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0008440	inositol trisphosphate 3-kinase activity	Molecular Function	TAS (1654894)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	TAS (1847047\|2176078)