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Gene Information
Gene ID:3726
Symbol:JUNB
Full Name:jun B proto-oncogene
Alias:AP-1
Organism:Homo sapiens (Human)
Chromosome:19
Genetic Location:19p13.2
Physical Location:12763309-12765124 on NC_000019.8
Gene Type:protein-coding
Orthologs:This gene has Mouse: 16477 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:X51345
Fold Change:-3.96
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Information
Original ID1:JUNB
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002229.2NP_002220.1NC_000019.8 range: 12763309..12765124
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000785chromatinCellular ComponentTAS (2513129)
GO:0005634nucleusCellular ComponentIEA
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0003702RNA polymerase II transcription factor activityMolecular FunctionTAS (2513129)
GO:0003713transcription coactivator activityMolecular FunctionTAS (2513129)
GO:0003714transcription corepressor activityMolecular FunctionTAS (2513129)
GO:0043565sequence-specific DNA bindingMolecular FunctionIEA
GO:0046983protein dimerization activityMolecular FunctionIEA
GO:0006357regulation of transcription from RNA polymerase II promoterBiological ProcessTAS (2513129)
Other Database Cross Links
NCBI Entrez Gene:3726
HGNC:6205
Ensembl:ENSG00000171223
MIM:165161
HPRD:01303
HuGE Navigator:3726
dbSNP:JUNB
GeneCard:JUNB
AceView:JUNB