ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

KCNMA1

Full Name:

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10q22.3

Physical Location:

78299365-79067582 on NC_000010.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 16531 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

KCNMA1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	NAS (7987297)
GO:0016020	membrane	Cellular Component	IEA
GO:0008076	voltage-gated potassium channel complex	Cellular Component	TAS (7993625)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0015269	calcium-activated potassium channel activity	Molecular Function	NAS (7987297)
GO:0015269	calcium-activated potassium channel activity	Molecular Function	IEA
GO:0030955	potassium ion binding	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005488	binding	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10692449)
GO:0006813	potassium ion transport	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0007269	neurotransmitter secretion	Biological Process	NR
GO:0007268	synaptic transmission	Biological Process	TAS (7993625)
GO:0006811	ion transport	Biological Process	IEA
GO:0006813	potassium ion transport	Biological Process	NAS (7987297)
GO:0006936	muscle contraction	Biological Process	NR