ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

LGALS3BP

Full Name:

lectin, galactoside-binding, soluble, 3 binding protein

Alias:

90K|MAC-2-BP

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q25

Physical Location:

74478931-74487655 on NC_000017.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		L13210
Fold Change:		2.27

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005567.2	NP_005558.1	NC_000017.9 range: 74478931..74487655, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	TAS (8390986)
GO:0016020	membrane	Cellular Component	IEA
GO:0005044	scavenger receptor activity	Molecular Function	TAS (8390986)
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0006968	cellular defense response	Biological Process	TAS (8034587)
GO:0007155	cell adhesion	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (8390986)