| Gene Information |
| Gene ID: | | 397 |
| Symbol: | | ARHGDIB |
| Full Name: | | Rho GDP dissociation inhibitor (GDI) beta |
| Alias: | | D4|GDIA2|GDID4|LYGDI|Ly-GDI|RAP1GN1 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 12 |
| Genetic Location: | | 12p12.3 |
| Physical Location: | | 14986216-15005828 on NC_000012.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | ARHGDIB | | Original ID2: | | L20688 |
| | Dataset Information | | Name: | | 11093800 | | Method: | | Microarray | | Tissue: | | SH-SY5Y neuroblastoma cells | | Phenotype: | | Ethanol response | | Publication: | | Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed | | Summary: | | We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005737 | cytoplasm | Cellular Component | TAS (16130169) | |
| GO:0005856 | cytoskeleton | Cellular Component | TAS (16130169) | |
| GO:0016023 | cytoplasmic membrane-bounded vesicle | Cellular Component | TAS (9113980) | |
| GO:0005094 | Rho GDP-dissociation inhibitor activity | Molecular Function | TAS (8262133) | |
| GO:0005096 | GTPase activator activity | Molecular Function | IEA | |
| GO:0007275 | multicellular organismal development | Biological Process | TAS (8434008) | |
| GO:0007266 | Rho protein signal transduction | Biological Process | TAS (8356058) | |
| GO:0007162 | negative regulation of cell adhesion | Biological Process | TAS (9113980) | |
| GO:0006955 | immune response | Biological Process | TAS (8356058) | |
| GO:0006928 | cell motility | Biological Process | TAS (16130169) | |
| GO:0030036 | actin cytoskeleton organization and biogenesis | Biological Process | TAS (8262133) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 397 |
| HGNC: | | 679 |
| Ensembl: | | ENSG00000111348 |
| MIM: | | 602843 |
| HPRD: | | 04162 |
| HuGE Navigator: | | 397 |
| dbSNP: | | ARHGDIB |
| GeneCard: | | ARHGDIB |
| AceView: | | ARHGDIB |
