ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

FADS1

Full Name:

fatty acid desaturase 1

Alias:

D5D|FADS6|FADSD5|FLJ38956|FLJ90273|LLCDL1|TU12

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q12.2-q13.1

Physical Location:

61323678-61340885 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 84575 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

FADS1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013402.3	NP_037534.2	NC_000011.8 range: 61323678..61340885, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	NAS (10601301)
GO:0005792	microsome	Cellular Component	NAS (10601301)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005624	membrane fraction	Cellular Component	NAS (10601301)
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0020037	heme binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IDA (10601301)
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0000248	C-5 sterol desaturase activity	Molecular Function	TAS (10601301)
GO:0045595	regulation of cell differentiation	Biological Process	NAS (10601301)
GO:0045449	regulation of transcription	Biological Process	NAS (10601301)
GO:0009267	cellular response to starvation	Biological Process	IDA (10601301)
GO:0008654	phospholipid biosynthetic process	Biological Process	TAS (10601301)
GO:0007267	cell-cell signaling	Biological Process	NAS (10601301)
GO:0006810	transport	Biological Process	IEA
GO:0006636	unsaturated fatty acid biosynthetic process	Biological Process	IDA (10601301)
GO:0006629	lipid metabolic process	Biological Process	IEA
GO:0046456	icosanoid biosynthetic process	Biological Process	TAS (10601301)