ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MAP3K3

Full Name:

mitogen-activated protein kinase kinase kinase 3

Alias:

MAPKKK3|MEKK3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q23.3

Physical Location:

59053532-59127401 on NC_000017.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 26406 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MAP3K3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043234	protein complex	Cellular Component	IDA (11256614)
GO:0005515	protein binding	Molecular Function	IPI (14743216)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEP (12761501)
GO:0004709	MAP kinase kinase kinase activity	Molecular Function	TAS (9006902)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IEP (12761501)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0000165	MAPKKK cascade	Biological Process	TAS (9006902)
GO:0046777	protein amino acid autophosphorylation	Biological Process	IDA (15001576)