| Gene Information |
| Gene ID: | | 4256 |
| Symbol: | | MGP |
| Full Name: | | matrix Gla protein |
| Alias: | | GIG36|MGLAP|NTI |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 12 |
| Genetic Location: | | 12p13.1-p12.3 |
| Physical Location: | | 14926093-14930094 on NC_000012.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | MGP | | Original ID2: | | H52207 |
| | Dataset Information | | Name: | | 11093800 | | Method: | | Microarray | | Tissue: | | SH-SY5Y neuroblastoma cells | | Phenotype: | | Ethanol response | | Publication: | | Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed | | Summary: | | We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment. |
| | Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005578 | proteinaceous extracellular matrix | Cellular Component | TAS (9916809) | |
| GO:0005576 | extracellular region | Cellular Component | IEA | |
| GO:0005201 | extracellular matrix structural constituent | Molecular Function | TAS (9916809) | |
| GO:0005509 | calcium ion binding | Molecular Function | IEA | |
| GO:0008147 | structural constituent of bone | Molecular Function | TAS (9916809) | |
| GO:0030154 | cell differentiation | Biological Process | IEA | |
| GO:0007605 | sensory perception of sound | Biological Process | IEA | |
| GO:0007275 | multicellular organismal development | Biological Process | IEA | |
| GO:0001502 | cartilage condensation | Biological Process | TAS (9916809) | |
| GO:0001503 | ossification | Biological Process | TAS (9916809) | |
| GO:0030500 | regulation of bone mineralization | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 4256 |
| HGNC: | | 7060 |
| Ensembl: | | ENSG00000111341 |
| MIM: | | 154870 |
| HPRD: | | 01112 |
| HuGE Navigator: | | 4256 |
| dbSNP: | | MGP |
| GeneCard: | | MGP |
| AceView: | | MGP |
