ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MLH1

Full Name:

mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3p21.3

Physical Location:

37009982-37067340 on NC_000003.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 17350 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MLH1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000249.2	NP_000240.1	NC_000003.10 range: 37009982..37067340

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IC (11809883)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003697	single-stranded DNA binding	Molecular Function	IDA (11809883)
GO:0005515	protein binding	Molecular Function	IPI (2414623\|11427529\|11429708\|14676842)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0032407	MutSalpha complex binding	Molecular Function	IDA (16403449)
GO:0032137	guanine/thymine mispair binding	Molecular Function	IMP (16713580)
GO:0030983	mismatched DNA binding	Molecular Function	IEA
GO:0006298	mismatch repair	Biological Process	TAS (8128251)
GO:0006298	mismatch repair	Biological Process	IMP (11555625)
GO:0006298	mismatch repair	Biological Process	IEA
GO:0045786	negative regulation of cell cycle	Biological Process	IEA