ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ATF4

Full Name:

activating transcription factor 4 (tax-responsive enhancer element B67)

Alias:

CREB-2|CREB2|TAXREB67|TXREB

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

22q13.1

Physical Location:

38246514-38248636 on NC_000022.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11911 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ATF4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	ISS
GO:0005737	cytoplasm	Cellular Component	ISS
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0003700	transcription factor activity	Molecular Function	TAS (12689582)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0016563	transcription activator activity	Molecular Function	NAS (9190894)
GO:0016563	transcription activator activity	Molecular Function	ISS
GO:0016563	transcription activator activity	Molecular Function	IMP (11960987)
GO:0046983	protein dimerization activity	Molecular Function	IEA
GO:0003704	specific RNA polymerase II transcription factor activity	Molecular Function	ISS
GO:0006950	response to stress	Biological Process	IEP (15314157)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	ISS
GO:0006350	transcription	Biological Process	IEA
GO:0006094	gluconeogenesis	Biological Process	ISS
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (15788408)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	ISS
GO:0006520	amino acid metabolic process	Biological Process	TAS (12689582)