ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

4771

Symbol:

NF2

Full Name:

neurofibromin 2 (merlin)

Alias:

ACN|BANF|SCH

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

22q12.2

Physical Location:

28329564-28424586 on NC_000022.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 18016 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

NF2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000268.3	NP_000259.1	NC_000022.9 range: 28329564..28424586
NM_016418.5	NP_057502.2	NC_000022.9 range: 28329564..28424586
NM_181825.2	NP_861546.1	NC_000022.9 range: 28329564..28424586
NM_181828.2	NP_861966.1	NC_000022.9 range: 28329564..28424586
NM_181829.2	NP_861967.1	NC_000022.9 range: 28329564..28424586
NM_181830.2	NP_861968.1	NC_000022.9 range: 28329564..28424586
NM_181831.2	NP_861969.1	NC_000022.9 range: 28329564..28424586
NM_181832.2	NP_861970.1	NC_000022.9 range: 28329564..28424586
NM_181833.2	NP_861971.1	NC_000022.9 range: 28329564..28424586

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA (17210637)
GO:0019898	extrinsic to membrane	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IDA (10401006)
GO:0005856	cytoskeleton	Cellular Component	TAS (8379998)
GO:0005769	early endosome	Cellular Component	IDA (10861283)
GO:0005737	cytoplasm	Cellular Component	IDA (9537418)
GO:0005730	nucleolus	Cellular Component	IDA (9537418)
GO:0005634	nucleus	Cellular Component	IDA (10401006)
GO:0042995	cell projection	Cellular Component	IEA
GO:0008092	cytoskeletal protein binding	Molecular Function	IEA
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	Biological Process	IDA (12444102)
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	Biological Process	IDA (12444102)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0046426	negative regulation of JAK-STAT cascade	Biological Process	IDA (12444102)
GO:0001953	negative regulation of cell-matrix adhesion	Biological Process	TAS (17210637)
GO:0030336	negative regulation of cell migration	Biological Process	TAS (17210637)
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	IMP (9537418)
GO:0022408	negative regulation of cell-cell adhesion	Biological Process	IDA (17210637)
GO:0014010	Schwann cell proliferation	Biological Process	IMP (17353411)
GO:0008285	negative regulation of cell proliferation	Biological Process	IMP (17210637)
GO:0008285	negative regulation of cell proliferation	Biological Process	IDA (12444102)
GO:0008156	negative regulation of DNA replication	Biological Process	IMP (17210637)
GO:0007605	sensory perception of sound	Biological Process	IEA
GO:0051496	positive regulation of stress fiber formation	Biological Process	IMP (9537418)