ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PAK2

Full Name:

p21 (CDKN1A)-activated kinase 2

Alias:

PAK65|PAKgamma

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3q29

Physical Location:

197951311-198043755 on NC_000003.10

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 29432 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PAK2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002577.4	NP_002568.2	NC_000003.10 range: 197951311..198043755

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	EXP (15234964)
GO:0016020	membrane	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0042802	identical protein binding	Molecular Function	IPI (16837009)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA (11805089)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	TAS (7744004)
GO:0006915	apoptosis	Biological Process	IEA
GO:0006469	negative regulation of protein kinase activity	Biological Process	TAS (10748018)
GO:0001558	regulation of cell growth	Biological Process	IEA
GO:0046777	protein amino acid autophosphorylation	Biological Process	IDA (11805089)