ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mapk9

Full Name:

mitogen-activated protein kinase 9

Alias:

SAPK

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

10q22

Physical Location:

35353485-35384318 on NC_005109.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5601 Symbol (Name): MAPK9 (mitogen-activated protein kinase 9)

Ortholog Status:

The human GeneID 5601 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		L27112
Fold Change:		8.6
Tissue:		Medial prefrontal (cingulate) cortex

Dataset Information

Name:		11772933
Method:		Microarray
Tissue:		Frontal cortex and amygdala
Phenotype:		Ethanol response
Publication:		Rimondini et al FASEB J. (2002) Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. PubMed
Summary:		Here we demonstrate that rats subjected to repeated cycles of intoxication and withdrawal develop a marked and long-lasting increase in voluntary ethanol intake. Exposure-induced but not spontaneous alcohol intake is antagonized by acamprosate, a compound clinically effective in human alcoholism. Expression analysis of cingulate cortex and amygdala reveals a set of long-term up-regulated transcripts in this model. Here lists the gene expression changes 3 wk after termination of 7 wk of intermittent ethanol exposure. Fold change values are ethanol exposed vs. control rats.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_017322.1	NP_059018.1	NC_005109.2 range: 35353485..35384318

Gene Ontology (GO) Annotation