ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SPOCK3

Full Name:

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

Alias:

HSAJ1454|TES-3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

4q32.3

Physical Location:

167891109-168392315 on NC_000004.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AJ001454
Fold Change:		2.26

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0004857	enzyme inhibitor activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0008191	metalloendopeptidase inhibitor activity	Molecular Function	IEA