ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

UBE2J1

Full Name:

ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)

Alias:

CGI-76|HSPC153|HSPC205|HSU93243|MGC12555|NCUBE1|Ubc6p

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6q15

Physical Location:

90093062-90119337 on NC_000006.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		UBE2J1
Original ID2:		R01227

Dataset Information

Name:		11093800
Method:		Microarray
Tissue:		SH-SY5Y neuroblastoma cells
Phenotype:		Ethanol response
Publication:		Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:		We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016021.2	NP_057105.2	NC_000006.10 range: 90093062..90119337, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0051246	regulation of protein metabolic process	Biological Process	IEA