ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ATP6V1A

Full Name:

ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A

Alias:

ATP6A1|ATP6V1A1|HO68|VA68|VPP2|Vma1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3q13.2-q13.31

Physical Location:

114948597-115013592 on NC_000003.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		L09235
Fold Change:		-3.02

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001690.2	NP_001681.2	NC_000003.10 range: 114948597..115013592

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8463241)
GO:0016469	proton-transporting two-sector ATPase complex	Cellular Component	TAS (8463241)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0046933	hydrogen ion transporting ATP synthase activity, rotational mechanism	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0046961	hydrogen ion transporting ATPase activity, rotational mechanism	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0006754	ATP biosynthetic process	Biological Process	IEA
GO:0015992	proton transport	Biological Process	IEA