ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Zwint

Full Name:

ZW10 interactor

Alias:

2010007E07Rik|2600001N01Rik|D10Ertd749e|Zwint-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

10 B5.3|10 38.0 cM

Physical Location:

72117642-72132536 on NC_000076.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11130 Symbol (Name): ZWINT (ZW10 interactor)

Ortholog Status:

The human GeneID 11130 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		D10Ertd749e
Original ID2:		D00073

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025635.3	NP_079911.1	NC_000076.5 range: 72117642..72132536

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000775	chromosome, pericentric region	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0007049	cell cycle	Biological Process	IEA
GO:0007067	mitosis	Biological Process	IEA
GO:0051301	cell division	Biological Process	IEA