ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PIGH

Full Name:

phosphatidylinositol glycan anchor biosynthesis, class H

Alias:

GPI-H

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

14q11-q24

Physical Location:

67125775-67136769 on NC_000014.7, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		PIGH
Original ID2:		L19783

Dataset Information

Name:		11093800
Method:		Microarray
Tissue:		SH-SY5Y neuroblastoma cells
Phenotype:		Ethanol response
Publication:		Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:		We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004569.3	NP_004560.1	NC_000014.7 range: 67125775..67136769, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	TAS (8900170)
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	Molecular Function	IEA
GO:0006464	protein modification process	Biological Process	TAS (8900170)
GO:0016254	preassembly of GPI anchor in ER membrane	Biological Process	EXP (11102867)