ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nell2

Full Name:

NEL-like 2 (chicken)

Alias:

A330108N19Rik|R75516|mel91

Organism:

Mus musculus (Mouse)

Chromosome:

Physical Location:

95049880-95359136 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4753 Symbol (Name): NELL2 (NEL-like 2 (chicken))

Ortholog Status:

The human GeneID 4753 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Nell2
Original ID2:		U59230

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016743.2	NP_058023.2	NC_000081.5 range: 95049880..95359136, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0007155	cell adhesion	Biological Process	IEA