ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

POLB

Full Name:

polymerase (DNA directed), beta

Alias:

MGC125976

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8p11.2

Physical Location:

42315186-42348469 on NC_000008.9

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 29240 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

POLB

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002690.1	NP_002681.1	NC_000008.9 range: 42315186..42348469

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005876	spindle microtubule	Cellular Component	IDA (15725623)
GO:0005737	cytoplasm	Cellular Component	IDA (15725623)
GO:0005654	nucleoplasm	Cellular Component	EXP (8978692\|9207062\|10559261\|11250913)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005622	intracellular	Cellular Component	IEA
GO:0016779	nucleotidyltransferase activity	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0031402	sodium ion binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008017	microtubule binding	Molecular Function	IDA (15725623)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (15520167)
GO:0003887	DNA-directed DNA polymerase activity	Molecular Function	TAS (8168825)
GO:0003887	DNA-directed DNA polymerase activity	Molecular Function	EXP (8978692\|11250913)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0006281	DNA repair	Biological Process	TAS (8168825)
GO:0006261	DNA-dependent DNA replication	Biological Process	TAS (8168825)