ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Prdx5

Full Name:

peroxiredoxin 5

Alias:

AOEB166|AOPP|Pmp20|Prdx6|PrxV

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 A|19 0.5 cM

Physical Location:

6981308-6984134 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 25824 Symbol (Name): PRDX5 (peroxiredoxin 5)

Ortholog Status:

The human GeneID 25824 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Prdx5
P Value:		0.001
Note:		Differentially expressed genes in brains of HAFT and LAFT mice. The P_value is the QTL P_value.

Dataset Information

Name:		12805289
Method:		Microarray and QTL
Tissue:		Whole brain
Phenotype:		Acute functional tolerance to ethanol
Publication:		Tabakoff et al. J Neurosci. (2003) Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors. PubMed
Summary:		We describe a novel approach that uses a combination of selective breeding, quantitative trait locus analysis, and DNA microarray technology to identify candidate genes for the complex phenotype of ethanol tolerance. Tolerance that develops during a single exposure to alcohol is defined as acute functional tolerance (AFT). Lines of mice to display high acute functional tolerance (HAFT mice) and low acute functional tolerance (LAFT mice) to the incoordinating effect of ethanol were used.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012021.2	NP_036151.1	NC_000085.5 range: 6981308..6984134, complement

Gene Ontology (GO) Annotation