Gene Information |
Gene ID: | | 54683 |
Symbol: | | Prdx5 |
Full Name: | | peroxiredoxin 5 |
Alias: | | AOEB166|AOPP|Pmp20|Prdx6|PrxV |
Organism: | | Mus musculus (Mouse) |
Chromosome: | | 19 |
Genetic Location: | | 19 A|19 0.5 cM |
Physical Location: | | 6981308-6984134 on NC_000085.5, complement |
Gene Type: | | protein-coding |
Human Ortholog: | | GeneID: 25824 Symbol (Name): PRDX5 (peroxiredoxin 5) |
Ortholog Status: | | The human GeneID 25824 is also in human dataset(s). |
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Gene in Ethanol Study Datasets |
Gene Information | Original ID1: | | Prdx5 | P Value: | | 0.001 | Note: | | Differentially expressed genes in brains of HAFT and LAFT mice. The P_value is the QTL P_value. |
| Dataset Information | Name: | | 12805289 | Method: | | Microarray and QTL | Tissue: | | Whole brain | Phenotype: | | Acute functional tolerance to ethanol | Publication: | | Tabakoff et al. J Neurosci. (2003) Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors. PubMed | Summary: | | We describe a novel approach that uses a combination of selective breeding, quantitative trait locus analysis, and DNA microarray technology to identify candidate genes for the complex phenotype of ethanol tolerance. Tolerance that develops during a single exposure to alcohol is defined as acute functional tolerance (AFT). Lines of mice to display high acute functional tolerance (HAFT mice) and low acute functional tolerance (LAFT mice) to the incoordinating effect of ethanol were used. |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0005737 | cytoplasm | Cellular Component | IEA | |
GO:0005739 | mitochondrion | Cellular Component | IDA (14651853) | |
GO:0005777 | peroxisome | Cellular Component | IEA | |
GO:0004601 | peroxidase activity | Molecular Function | IEA | |
GO:0016209 | antioxidant activity | Molecular Function | IEA | |
GO:0016491 | oxidoreductase activity | Molecular Function | IEA | |
GO:0051920 | peroxiredoxin activity | Molecular Function | IEA | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 54683 |
MGI: | |
Ensembl: | | ENSMUSG00000024953 |
dbSNP: | | Prdx5 |
AceView: | | Prdx5 |